Studies of Phosphatidylinositol 3 Kinase (PI3K) Signaling Pathway in Mammalian Ovarian Follicle Activation and Development
نویسنده
چکیده
................................................................................................... 5 PUBLICATION LIST........................................................................................6 INTRODUCTION.............................................................................................7 1. THE MAMMALIAN OVARY........................................................................... 9 1.1 Follicle Formation....................................................................................... 10 1.2 Classification of Follicles............................................................................... 11 1.3 Follicular Activation and Early Development...................................................... 12 GDF9 and BMP15........................................................................................ 13 Smads...................................................................................................... 14 1.4 Regulation of Follicular Development by Follicle Stimulating Hormone (FSH)............15 1.5 Ovulation and Luteinizing Hormone (LH)......................................................... 16 1.6 The Corpus Luteum (CL)..............................................................................18 1.7 Follicular Atresia........................................................................................ 18 2. THE PHOSPHOTIDYLINOSITOL 3 KINASE (PI3K) PATHWAY.......................... 20 2.
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